Mary G. PRIEVE,Michael E. HOUSTON, JR.,Pierrot HARVIE,Sean D. MONAHAN,Pierrot HARVIE,P‧哈維,Sean D. MONAHAN,S‧D‧莫納漢
申请号:
HK18108250
公开号:
HK1248548A1
申请日:
2018.06.27
申请国别(地区):
HK
年份:
2018
代理人:
摘要:
Disclosed are methods for delivering a therapeutic or diagnostic agent to the cytosol of a cell in a subject. The disclosed methods generally include administering to the subject an effective amount of a lipid nanoparticle comprising the therapeutic or diagnostic agent and an effective amount of a membrane-destabilizing polymer. Also disclosed are related compositions and delivery systems.