Mary G. PRIEVE,Michael E. HOUSTON, JR.,Pierrot HARVIE,Sean D. MONAHAN
申请号：
US15545302
公开号：
US20180221402A1
申请日:
2016.01.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed are methods for delivering a therapeutic or diagnostic agent to the cytosol of a cell in a subject. The disclosed methods generally include administering to the subject an effective amount of a lipid nanoparticle comprising the therapeutic or diagnostic agent and an effective amount of a membrane-destabilizing polymer. Also disclosed are related compositions and delivery systems.
