PRIEVE, MARY G.,HOUSTON, MICHAEL E., JR.,HARVIE, PIERROT,MONAHAN, SEAN D.
申请号:
CA2974503
公开号:
CA2974503A1
申请日:
2016.01.21
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Disclosed are methods for delivering a therapeutic or diagnostic agent to the cytosol of a cell in a subject. The disclosed methods generally include administering to the subject an effective amount of a lipid nanoparticle comprising the therapeutic or diagnostic agent and an effective amount of a membrane-destabilizing polymer. Also disclosed are related compositions and delivery systems.