PRIEVE MARY G,HOUSTON JR MICHAEL E,HARVIE PIERROT,MONAHAN SEAN D
申请号:
IN201747028808
公开号:
IN201747028808A
申请日:
2017.08.14
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
Disclosed are methods for delivering a therapeutic or diagnostic agent to the cytosol of a cell in a subject. The disclosed methods generally include administering to the subject an effective amount of a lipid nanoparticle comprising the therapeutic or diagnostic agent and an effective amount of a membrane destabilizing polymer. Also disclosed are related compositions and delivery systems.