CAI, SUI XIONG,TIAN, YE EDWARD,DONG, HAIJUN,XU, QINGBING,WU, LIZHEN,LIU, LIJUN,JIANG, YANGZHEN,BAO, QINGLI,WANG, GUOXIANG,YIN, FENG,GU, CHENGYUN,HU, XIUHUA,WANG, XIAOZHU,KANG, SISHUN,CHEN, SHENGZHI
申请号：
EP12765230
公开号：
EP2709990A4
申请日:
2012.03.31
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
Disclosed are 1-(arylmethyl)quinazoline-2,4(1H,3H)-diones thereof, represented by the Formula (I) wherein Ar, R1-R6 are defined herein. Compounds having Formula (I) are PARP inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of PARP activity.
