KEPKA, STANLEY W.,MO, Y. JOSEPH,WANG, HANG-YONG,LU, MINGQI,PFISTER, WILLIAM R.
申请号：
CA2519705
公开号：
CA2519705C
申请日:
2004.03.22
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
A dual action antifungal nail coat composition and method of use forameliorating or preventing fungal infection of the nails, and onychomycosis,in particular, is disclosed. Composition embodiments in the form of one-coattype and two-coat type suitable for daily fungicidal regimens are disclosed. Apreferred antifungal nail coat composition comprises an effective fungicidalamount of antifungal agent, a permeation enhancing amount of a substantiallynon-volatile, permeation enhancer, a film-forming amount of a hydrophilicpolymer, and a pharmaceutically acceptable, volatile carrier. The compositionprovides a substantially water-soluble fungicidal coating on contacting afungally susceptible or infected nail.
