KIM NAM HO,LEE JIN YOUNG,KIM JAE SUN,LEE NAM KYU,JANG WOO JAE,OH JOON GYO,LEE YOON JUNG,KIM WOONG SILK,SUNG JIN HEUNG,UM KEY AN
申请号:
IN2587/MUMNP/2008
公开号:
IN276298B
申请日:
2008.12.04
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.