Woong Sik Kim;Woo Jae Jang;Joon Gyo Oh;Key An Um;Nam Kyu Lee;Nam Ho Kim;Jae-Sun Kim;Jin-Heung Sung;Jin Young Lee;Yoon-Jung Lee
发明人:
Nam Ho Kim,Jin Young Lee,Jae-Sun Kim,Nam Kyu Lee,Woo Jae Jang,Joon Gyo Oh,Yoon-Jung Lee,Woong Sik Kim,Jin-Heung Sung,Key An Um
申请号：
US12301700
公开号：
US08791152B2
申请日:
2007.05.22
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.
