KIM, NAM HO,UM, KEY AN,LEE, JIN YOUNG,KIM, JAE-SUN,LEE, NAM KYU,JANG, WOO JAE,OH, JOON GYO,LEE, YOON-JUNG,KIM, WOONG SIK,SUNG, JIN-HEUNG
申请号:
MYPI 20084753
公开号:
MY149627A
申请日:
2007.05.22
申请国别(地区):
MY
年份:
2013
代理人:
摘要:
THE PRESENT INVENTION RELATES TO A STABLE PHARMACEUTICAL COMPOSITION FOR INJECTION CONTAINING DOCETAXEL AND A METHOD OF PREPARING THE SAME. MORE PARTICULARLY, THE PRESENT INVENTION RELATES TO A PHARMACEUTICAL COMPOSITION FOR INJECTION CONTAINING DOCETAXEL HAVING BETTER STORAGE STABILITY THAN CONVENTIONAL MEDICATIONS, WHICH IS PREPARED BY DISSOLVING DOCETAXEL, A WATER-INSOLUBLE COMPOUND, IN DISTILLED WATER AFTER MIXING IT WITH CYCLODEXTRIN (CD) AND A WATER-SOLUBLE POLYMER SUCH AS HYDROXYPROPYL METHYLCELLULOSE (HPMC), POLYETHYLENE GLYCOL (PEG) OR POLYVINYLPYRROLIDONE (PVP) AND LYOPHILIZING THE MIXTURE, AND A METHOD OF PREPARING THE SAME.