Oh, Joon Gyo,Kim, Woong Sik,Um, Key An,Kim, Nam Ho,Jang, Woo Jae,Kim, Jae-Sun,Sung, Jin-Heung,Lee, Yoon-Jung,Lee, Nam Kyu,Lee, Jin Young
申请号:
AU2007252371
公开号:
AU2007252371B2
申请日:
2007.05.22
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.