Brian Yinge Zhao;Margarita Ren;Cornell University of Center for Technology Licensing at Cornell University (CTL)
发明人:
Ren, Margarita,Zhao, Brian Yinge,Szeto, Hazel H.,Birk, Alexander V.,Szabo, Paul
申请号：
AU2020203424
公开号：
AU2020203424A1
申请日:
2020.05.25
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2020203424A120200611.pdf#####ABSTRACT The present disclosure provides aromatic-cationic peptides and methods of using the same. The methods comprise the use of the aromatic-cationic peptides in reducing the effects of toxic beta amyloid (AP) peptides including blocking the accumulation of extracellular AP oligomers, inhibiting Ap-mediated oxygenase activity, reducing Ap-induced mitochondrial dysfunction and/or preventing Ap-induced neuronal apoptosis.
