Hazel H. SZETO,Alexander V. BIRK,Paul SZABO,Brian Yinge ZHAO,Margarita REN
申请号：
US15025612
公开号：
US20160375088A1
申请日:
2014.09.29
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present disclosure provides aromatic-cationic peptides and methods of using the same. The methods comprise the use of the aromatic-cationic peptides in reducing the effects of toxic beta amyloid (Aβ) peptides including blocking the accumulation of extracellular Aβ oligomers, inhibiting Aβ-mediated oxygenase activity, reducing Aβ-induced mitochondrial dysfunction and/or preventing Aβ-induced neuronal apoptosis.
