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Reduced-odor thiol compositions
专利权人:
Mario W. Medri
发明人:
Mario W. Medri
申请号:
US12959807
公开号:
US08440219B2
申请日:
2010.12.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides compositions for and methods of delivering a therapeutically-effective dose of a malodorous, sulfide or disulfide group-containing compound, for example glutathione (reduced) and/or glutathione disulfide, in a vehicle that is effective to reduce the unpleasant odor and/or taste of the compound. The invention further provides methods for reducing the amount of oxidation occurring when sulfide group-containing compounds, such as glutathione, are incorporated into sugar and or sugar-free hard candies without subjecting the glutathione to thermal and or moisture degradation where degradation is expressed as oxidation. The invention further provides vehicle compositions including the protected sulfide group-containing compounds and their use as medicaments. The sulfide group-containing compounds are protected from degradation by their dispersion into fats, oils, and/or fractionated or partially hydrogenated oils prior to their blending into the vehicle.
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