Obschestvo S Ogranichennoy Otvetstvennostju "Iva Farm"
发明人:
BALAZOVSKIJ, Mark Borisovich,ANTONOV, Viktor Georgievich,IGNATENKO, Oleg Aleksandrovich
申请号：
AU2018370441
公开号：
AU2018370441A1
申请日:
2018.07.17
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Pharmaceutical composition comprising glutathione disulphide or pharmaceutically acceptable organic or inorganic salt thereof and glutathione disulfide S-oxide of the following structure: (I) or pharmaceutically acceptable organic or inorganic salt thereof for eliminating dose-related toxicity and enhancing the therapeutic activity of a pharmacologically active compound in the treatment of infectious and non-infectious diseases is provided. Typically, the composition comprises glutathione disulfide S-oxide in an amount of 0.01-10% by weight of the total composition, and additionally a metal (Me) in the form of coordination compound(s) containing Me-S-glutathione bond, said metal is selected from the platinum group, typically it is platinum. The amount of d-metal coordination compound administered to a patient can be 10
