MATHES CHRISTIAN SWITZERLAND,FOULKES MICHAEL SWITZERLAND,KESSELGRUBER MARTIN SWITZERLAND
申请号：
IN4674/DELNP/2011
公开号：
IN2011DN04674A
申请日:
2011.06.17
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drag substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmetric catalytic reduction and transfer hydrogenation, thereby providing an improved route to forming drug substances such as rivastigimine and rivastigimine hydrogen tartrate.
