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Process and methods for the preparation of optically active cis-2-hydroxymethyl-4-(cytosin-1′-yl)-1,3-oxathiolane or pharmaceutically acceptable salts thereof
专利权人:
Alex Cimpoia
发明人:
Alex Cimpoia,Dan Simion
申请号:
US13166242
公开号:
US08399655B2
申请日:
2011.06.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
There is provided a method for resolving a compound of formula III, in the cis configuration:There is also provided a process for producing optically active compound of formula I or II:wherein: R1, R2, R3 are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.
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