Vikas Chandra Rai,Pankaj Kumar Naithani,Arvind Yekanathsa Merwade,KESHAV DEO
申请号：
IN191/MUM/2010
公开号：
IN2010MU00191A
申请日:
2010.01.25
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
The present invention relates to a process of preparation of Dextromethorphan and its salts thereof. The process involves the deformylation of N-Formyl-3-methoxymorphinan in presence of base followed by methylating 3-methoxymorphinan to yield Dextromethorphan and subsequently its conversion to pharmaceutically accepted salt. The process is very economical, eco-friendly, free from use of hazardous, costly reagent and easily scalable at industrial scale.
