Ingrid Henriksen,Svein Kvale,Ole Johannes TOKERUD,Sontum Per,Marit SWAERD-NORDMO KISERUD
申请号：
US15126368
公开号：
US20170080113A1
申请日:
2015.03.31
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to a method of preparation of ultrasound contrast agent precursors comprising phospholipid-stabilised perfluorobutane microbubbles. The method is amenable to commercial scale manufacture, and provides more consistent vial-to-vial yields and size distribution of said microbubbles. Also provided are methods of preparing kits and ultrasound contrast agents using the method of the invention.
