HENRIKSEN, INGRID,KVALE, SVEIN,TOKERUD, OLE, JOHANNES,PER, SONTUM,SWAERD-NORDMO KISERUD, MARIT
申请号：
SG11201607455V
公开号：
SG11201607455VA
申请日:
2015.03.31
申请国别(地区):
SG
年份:
2016
代理人:
摘要：
The present invention relates to a method of preparation of ultrasound contrast agent precursors comprising phospholipid-stabilised perfluorobutane microbubbles. The method is amenable to commercial scale manufacture, and provides more consistent vial-to-vial yields and size distribution of said microbubbles. Also provided are methods of preparing kits and ultrasound contrast agents using the method of the invention.
