MORIN PAUL E,COHEN DANIEL,MUKHERJEE RANJAN,REILLY TIMOTHY P,CHRISTIAN ROSE C,LIPOVSEK DASA,CAMPHAUSEN RAY,KRUPINSKI JOHN
申请号:
IN201717018139
公开号:
IN201717018139A
申请日:
2017.05.23
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
Modified FGF 21 polypeptides and uses thereof are provided for example for the treatment of diseases associated with fibrosis. Modified FGF 21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide optionally modified with at least one non naturally encoded amino acid and/or optionally fused to a fusion partner.