Morin, Paul E.,Cohen, Daniel,Mukherjee, Ranjan,Reilly, Timothy P.,Christian, Rose C.,Lipovsek, Dasa,Camphausen, Ray,Krupinski, John
申请号:
AU2015335603
公开号:
AU2015335603A1
申请日:
2015.10.23
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.