Paul E. Morin,Daniel Cohen,Ranjan Mukherjee,Timothy P. Reilly,Rose C. Christian,Dasa Lipovsek,Ray Camphausen,John Krupinski
申请号：
US15979881
公开号：
US10377806B2
申请日:
2018.05.15
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
