THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人:
SIEGWART, DANIEL J.,HAO, JING,ZHOU, KEJIN,MILLER, JASON,KOS, PETRA,XUE, LIAN
申请号:
CA2970177
公开号:
CA2970177A1
申请日:
2015.12.08
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Polymers produced by ring opening polymerization which comprises an amino group that can be used in compositions to deliver a nucleic acid such as a miRNA or a siRNA. In some embodiments, compositions which comprise the polymers described herein and a nucleic acid are also provided herein. In some embodiments, these compositions are used to silence one or more genes in vivo or treat a disease or disorder.