Daniel J. SIEGWART,Jing HAO,Kejin ZHOU,Jason MILLER,Petra KOS,Lian XUE
申请号:
US15261245
公开号:
US20170100482A1
申请日:
2016.09.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Polymers produced by ring opening polymerization which comprises an amino group that can be used in compositions to deliver a nucleic acid such as a miRNA or a siRNA. In some embodiments, compositions which comprise the polymers described herein and a nucleic acid are also provided herein. In some embodiments, these compositions are used to silence one or more genes in vivo or treat a disease or disorder.