The Board of Regents of the University of Texas System
发明人:
Siegwart, Daniel J.,Hao, Jing,Zhou, Kejin,Miller, Jason,Kos, Petra,Xue, Lian
申请号:
AU2015360794
公开号:
AU2015360794A1
申请日:
2015.12.08
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Polymers produced by ring opening polymerization which comprises an amino group that can be used in compositions to deliver a nucleic acid such as a miRNA or a siRNA. In some embodiments, compositions which comprise the polymers described herein and a nucleic acid are also provided herein. In some embodiments, these compositions are used to silence one or more genes in vivo or treat a disease or disorder.