HEINELT, UWE,WEHNER, VOLKMAR,HERRMANN, MATTHIAS,SCHOENAFINGER, KARL,STEINHAGEN, HENNING,SCHEIPER, BODO
申请号：
ES09708289
公开号：
ES2379447T3
申请日:
2009.01.23
申请国别(地区):
ES
年份:
2012
代理人:
摘要：
Compound of the formula I and / or all stereoisomeric or tautomeric forms of the compound of the formula I and / or mixtures of these forms in any proportion, and / or a physiologically tolerable salt of the compound of the formula I, wherein Q1 represents atom of hydrogen, -C1-C6-alkyl, -C3-C6-cycloalkyl, -OH, -O-C1-C6-alkyl or -O-C3-C6-alkyl, where alkyl and cycloalkyl are in each unsubstituted case is either mono-, di- or trisubstituted independently of each other with -C1-C6 alkyl, -C3-C6 alkyl, OH, -O-C1-C6 alkyl or - O-cycloalkyl (C3-C6), where in alkyl or cycloalkyl the hydrogen atoms can be totally or partially replaced by fluorine, Q2 and Q3 are the same or different and independently of each other represent hydrogen atom, -alkyl (C1 -C6) or - (C3-C6) cycloalkyl, where in alkyl or cycloalkyl hydrogen atoms can be totally or partially replaced by R fluorine, R1, R2 and R3 are the same or different and independently of each other represent hydrogen atom, -C1-C6 alkyl, -C3-C6 cycloalkyl, -O-C1-C8 alkyl, - O-cycloalkyl (C3-C6), -alkylene (C0-C4) -C (O) -N (R11) -R12, -alkylene (C0-C4) -C (O) -O-R11, -alkylene (C0 -C4) -C (O) -R11, -alkylene (C0-C4) -N (R11) -R12, -alkylene (C0-C4) N (R11) -C (O) -R12, halogen, OH, - CN, -NO2, -SO2CH3, -SO2CF3, -SF5, -Si [(C1-C4) alkyl], 3-alkyl (C1-C6) -Oalkyl (C1-C6), -O-alkylene (C1-C6) -O-C1-C6 alkyl, -O-alkylene (C0-C4) -aryl (C6-C14), wherein aryl is unsubstituted or is mono-, di- or trisubstituted independently of each other with - O-C1-C6 alkyl, -C1-C4 alkyl, OH, cycloalkyl (C3-C6) or -O-cycloalkyl (C3-C6), -O-alkylene (C1-C4) -cycloalkyl (C3 -C6), -Het (C4-C15), where Het is unsubstituted or is mono-, di- or trisubstituted independently of each other with -alkyl (C1-C4), -cycloalkyl (C3-C6), OH, -O-alkyl (C1-C6) or -O-cycloalkyl (C3-C6), or -O-alkylene (C1-C6) -O-alkylene (C1-C6) -O-alkyl (C1-C6), wherein alkyl , alkylene and cycloalkyl are in each case unsubstituted or are mono-, di- or trisubstituted independently of
