DERIVATI 2-HIDROKSI-1-{4-[(4-FENILFENIL)KARBONIL]PIPERAZIN-1-IL}ETAN-1-ONA I SRODNI SPOJEVI KAO INHIBITORI SINTAZE MASNIH KISELINA (FASN) ZA LIJEČENJE RAKA
Bair, Kenneth W.,Lancia, David R.,Li, Hongbin,Loch, James,Lu, Wei,Martin, Matthew W.,Millan, David S.,Schiller, Shawn E.r.,Tebbe, Mark J.
申请号：
HRP20191860
公开号：
HRP20191860T1
申请日:
2019.10.14
申请国别(地区):
HR
年份:
2019
代理人:
摘要：
The present invention relates to a list of specific 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (FAS or FASN) inhibitors for treating cancer and pharmacutical compositions thereof .An illustrative compound of the invention is shown below:
