DERIVATI 2-HIDROKSI-1-{4-[(4-FENILFENIL)KARBONIL]PIPERAZIN-1-IL}ETAN-1-ONA I SRODNA JEDINJENJA KAO INHIBITORI SINTAZE MASNIH KISELINA (FASN) ZA LEČENJE KANCERA
BAIR, KENNETH, W.,LANCIA, DAVID R., JR.,LI, HONGBIN,LOCH, JAMES,LU, WEI,MARTIN, MATTHEW, W.,MILLAN, DAVID, S.,SCHILLER, SHAWN, E.R.,TEBBE, MARK, J.
申请号:
RSP20191323
公开号:
RS59411B1
申请日:
2014.03.11
申请国别(地区):
RS
年份:
2019
代理人:
摘要:
The present invention relates to a list of specific 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (FAS or FASN) inhibitors for treating cancer and pharmacutical compositions thereof .An illustrative compound of the invention is shown below: