Pochodne 2-hydroksy-1-{4-[(4-fenylofenylo)karbonylo]piperazyn-1-ylo}etan-1-onu i związki pokrewne jako inhibitory syntazy kwasu tłuszczowego (FASN) do leczenia nowotworu
BAIR, KENNETH W.,LANCIA, DAVID R. JR.,LI, HONGBIN,LOCH, JAMES,LU, WEI,MARTIN, MATTHEW W.,MILLAN, DAVID S.,SCHILLER, SHAWN E.R.,TEBBE, MARK J.
申请号：
PL14779048
公开号：
PL2968316T3
申请日:
2014.03.11
申请国别(地区):
PL
年份:
2019
代理人:
摘要：
The present invention relates to a list of specific 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (FAS or FASN) inhibitors for treating cancer and pharmacutical compositions thereof .An illustrative compound of the invention is shown below:
