2-HYDROXY-1- {4 - [(4-PHENYLPHENYL) CARBONYL] PIPERAZIN-1-YL} ETHAN-1-ON DERIVATIVES AND RELATED COMPOUNDS LIKE FATHERIC ACID SYNTHASE (PHASN) INHIBITORS FOR TREATMENT
BAIR, Kenneth, W.,LI, Hongbin,LOCH, James,LU, Wei,MARTIN, Matthew, W.,MILLAN, David, S.,SCHILLER, Shawn, E.r.,TEBBE, Mark, J.,LANCIA, David R., Jr.
申请号:
DK14779048
公开号:
DK2968316T3
申请日:
2014.03.11
申请国别(地区):
DK
年份:
2019
代理人:
摘要:
The present invention relates to a list of specific 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (FAS or FASN) inhibitors for treating cancer and pharmacutical compositions thereof .An illustrative compound of the invention is shown below: