AHMAD, OMAR KHALED,BROWN, STEPHEN PAUL,DIRICO, KENNETH JOHN,DUSHIN, RUSSELL,FILZEN, GARY FREDERICK,PUTHENVEETIL, SUJIET,STROP, PAVEL,SUBRAMANYAM, CHAKRAPANI,TUMEY, LAWRENCE N.
申请号:
CA3051038
公开号:
CA3051038A1
申请日:
2018.01.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention is directed to novel calicheamicin derivatives useful as payloads in antibody-drug-conjugates (ADC's), and to payload-linker compounds and ADC compounds comprising the same; to pharmaceutical compositions comprising the same and to methods for using the same to treat pathological conditions such as cancer.