DE KOCK, HERMAN AUGUSTINUS,戴寇克,戴寇克,JONCKERS, TIM HUGO MARIA,周克斯,周克斯,LAST, STEFAAN JULIEN,蓝斯特,藍斯特,BOONANTS, PAUL JOZEF GABRIEL MARIA,巴纳斯,巴納斯,SURLERAUX, DOMINIQUE LOUIS NESTOR GHISLAIN,苏雷瑞,蘇雷瑞,WIGERINCK
申请号：
TW095143660
公开号：
TWI432438B
申请日:
2006.11.27
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
The present invention concems substituted aminophenylsulfonamide compounds and derivatives their use as protease inhibitors, in particular as broadspectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions anddiagnostic kits comprising them. The present invention also concerns combinations of the present substitutd aminophenylsulfonamide compounds and derivatives with another anti-retroviral agnet. It further relates th their use in assays as reference compounds oras reagents.本發明涉及經取代之胺基苯基磺醯胺化合物及衍生物,它們作為蛋白酶抑制劑之用途,特別是作為廣效HIV蛋白酶抑制劑,用於製備它們還有藥學組成物之方法以及含有它們之診斷套組。本發明亦涉及該經取代胺基苯基磺醯胺化合物及衍生物與另一抗逆轉錄病毒劑的組合。其進一步有關於它們在分析中作為參考化合物或作為試劑的用途。
