DE KOCK, HERMAN AUGUSTINUS,戴寇克,戴寇克,JONCKERS, TIM HUGO MARIA,周克斯,周克斯,LAST, STEFAAN JULIEN,蓝斯特,藍斯特,BOONANTS, PAUL JOZEF GABRIEL MARIA,巴纳斯,巴納斯,SURLERAUX, DOMINIQUE LOUIS NESTOR GHISLAIN,苏雷瑞,蘇雷瑞,WIGERINCK
申请号：
TW095143659
公开号：
TWI385173B
申请日:
2006.11.27
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention concerns substituted aminophenylsulfonamide compounds, their use as protease inhibitors, in particular as broad-spectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present substituted aminophenylsulfonamide compounds with another anti-retroviral agent. It further relates to their use in assays as reference compounds or as reagents.本發明有關經取代之胺基苯基磺醯胺化合物、其作為蛋白酶抑制劑-尤其是作為廣效型HIV蛋白酶抑制劑-之用途、其製備方法及包含該等化合物之醫藥組成物及診斷套組。本發明亦有關本發明經取代之胺基苯基磺醯胺化合物與另一種抗逆轉錄病毒劑之組合物。另外有關其於檢測中作為參考化合物或作為試劑之用途。
