Dry powder formulations for inhalation and their use in the treatment diseases and conditions. The formulation contains a uniform blend of a first spray dried powder and a second spray dried powder. The first spray dried powder contains spray dried particles of a therapeutically active ingredient dispersed in a pharmaceutically acceptable hydrophobic excipient. The second spray dried powder contains spray dried particles formed from a pharmaceutically acceptable hydrophobic excipient but are substantially free of any therapeutically active ingredient. The active ingredient in the first spray dried powder is loaded sufficiently high to compensate for the second spray dried powder being substantially free of any active ingredient. A process for preparing such formulations is also described.