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スプレーブレンディングによるスプレー乾燥製剤の脱アモルファス化
专利权人:
ノバルティス アーゲー
发明人:
ウィアーズ,ジェフリー,フアン,ダニエル,タララ,トーマス,ミラー,ダンフォース
申请号:
JP2015562483
公开号:
JP6232079B2
申请日:
2014.03.11
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
Dry powder formulations for inhalation and their use in the treatment diseases and conditions. The formulation contains a uniform blend of a first spray-dried powder and a second spray-dried powder. The first spray-dried powder contains spray-dried particles of a therapeutically active ingredient dispersed in a pharmaceutically acceptable hydrophobic excipient. The second spray-dried powder contains spray-dried particles formed from a pharmaceutically acceptable hydrophobic excipient but are substantially free of any therapeutically active ingredient. The active ingredient in the first spray-dried powder is loaded sufficiently high to compensate for the second spray-dried powder being substantially free of any active ingredient. A process for preparing such formulations is also described.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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