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COMPOSITIONS DE VIRUS HERPÉTIQUE ET PROCÉDÉS ASSOCIÉS
专利权人:
Sanofi Pasteur Limited;Sanofi Pasteur Biologics, LLC
发明人:
申请号:
EP13793902.1
公开号:
EP2852662B1
申请日:
2013.05.21
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compositions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
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