Stephen Anderson,Simon Delagrave,John Hamberger,Qinglian Li,Sophia Mundle,Nausheen Rahman
申请号：
US14402678
公开号：
US20150150964A1
申请日:
2013.05.21
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compositions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
