A compound of Formula (I): ** Formula ** wherein: R1 is NR4R5, a C1 to C6 alkoxy, which is not substituted or is substituted with one or more of halogen, OH, alkoxy, NH2, (alkyl) amino -, di (alkyl) amino-, (alkyl) C (O) N (C1-C3 alkyl) -, (alkyl) carboxyamido-, HC (O) NH-, H2NC (O) -, (alkyl) NHC (O ) -, di (alkyl) NC (O) -, CN, C (O) OH, (alkoxy) carbonyl-, (alkyl) C (O) -, aryl, heteroaryl, cycloalkyl, haloalkyl, amino (C1-C6 alkyl) ) -, (alkyl) carboxy-, carboxyamidoalkyl-, or NO2, a C6 to C14 aryl, which is unsubstituted or substituted by one or more of alkyl, halogen, haloalkyl, alkoxy, haloalkoxy, OH, hydroxyalkyl, -O- (hydroxyalkyl), -O- (alkyl) -C (O) OH, - (alkyl) - (alkoxy) -halogen, NH2, aminoalkyl-, dialkylamino-, C (O) OH, -C (O) O- ( alkyl), -OC (O) (alkyl), -O- (alkyl) -N (alkyl) (alkyl), N-alkylamido-, -C (O) NH2, (alkyl) amido-, NO2, (aryl) alkyl, aryloxy, heteroaryloxy, (aryl) amino, (alkoxy) carbonyl-, (alkyl) amido-, (alkyl) amino, alkylcarboxyl-, (alkyl) carboxyamido-, (ari l) alkyl-, (aryl) amino-, cycloalkenyl, heteroaryl, (heteroaryl) alkyl-, heterocyclyl, -O- (heterocyclyl), heterocyclyl (alkyl) -, (hydroxyalkyl) NH-, (hydroxyalkyl) 2N, -SO2 ( alkyl) or a spiro substituent, a heteroaryl, which is unsubstituted or substituted with one or more of C1-C6 alkyl, halogen, haloalkyl, OH, CN, hydroxyalkyl, NH2, aminoalkyl-, dialkylamino-, C (O) OH , -C (O) O- (alkyl), -OC (O) (alkyl), N-alkylamido-, - C (O) NH2, (alkyl) amido-, -NO2, (aryl) alkyl, alkoxy, aryloxy , heteroaryloxy, (aryl) amino, (alkoxy) carbonyl-, (alkyl) amido-, (alkyl) amino, aminoalkyl-, alkylcarboxyl-, (alkyl) carboxyamido-, (aryl) alkyl-, (aryl) amino-, cycloalkenyl , heteroaryl, (heteroaryl) alkyl-, heterocyclyl, heterocyclyl (alkyl) -, (hydroxyalkyl) NH-, (hydroxyalkyl) 2N or a spiro substituent, a 3-10 membered monocyclic or bicyclic cycloalkyl, which is unsubstituted or substituted with one or more of halogen, NH2, (alkyl) NH, (alkyl) (alkyl) N-, -N (alkyl) C (O) (alkyl), -
