Bruce Levine;Chrystal Paulos;James L. Riley;Carl H. June
发明人:
James L. Riley,Chrystal Paulos,Carl H. June,Bruce Levine
申请号：
US13576249
公开号：
US09133436B2
申请日:
2011.02.04
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention includes compositions and methods for generating and expanding therapeutic Th17 cells. The invention includes contacting T cells with a composition comprising a first agent that is capable of providing a primary activation signal to T cells and a second agent that is capable of activating ICOS on T cells in the presence of Th-17 polarizing agents.
