James L. Riley,Chrystal Paulos,Carl H. June,Bruce L. Levine
申请号:
US15986538
公开号:
US20180371414A1
申请日:
2018.05.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention includes compositions and methods for generating and expanding therapeutic Th17 cells. The invention includes contacting T cells with a composition comprising a first agent that is capable of providing a primary activation signal to T cells and a second agent that is capable of activating ICOS on T cells in the presence of Th-17 polarizing agents.