RODRIGUEZ-BORLADO, Luis,HEMMATI, Houman,JOHNSON, Jennifer, L.,PECK, Kiel, A.,SMITH, Rachel, R.,MARBAN, Linda
申请号:
EP17767367
公开号:
EP3429557A4
申请日:
2017.03.14
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to a method of treating a chemical injury of the eye, in particular alkali bum of the cornea, as well as ocular GVHD and similar inflammatory ocular conditions, with extracellular vesicles, in particular exosomes obtained from human cardiospheres or cardiosphere-derived cells. The present invention also provides a formulation comprising extracellular vesicles, in particular exosomes obtained from human cardiospheres or cardiosphere-derived cells, for subconjunctival or topical administration to the eye in the treatment of a chemical injury of the eye, in particular alkali bum of the cornea, as well as ocular GVHD and similar inflammatory ocular conditions.