Luis Rodriguez-Borlado,Houman Hemmati,Jennifer L. Johnson,Kiel A. Peck,Rachel R. Smith,Linda Marban
申请号：
US16084186
公开号：
US20200289580A1
申请日:
2017.03.14
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a method of treating a chemical injury of the eye, in particular alkali burn of the cornea, as well as ocular GVHD and similar inflammatory ocular conditions, with extracellular vesicles, in particular exosomes obtained from human cardiospheres or cardiosphere-derived cells. The present invention also provides a formulation comprising extracellular vesicles, in particular exosomes obtained from human cardiospheres or cardiosphere-derived cells, for subconjunctival or topical administration to the eye in the treatment of a chemical injury of the eye, in particular alkali burn of the cornea, as well as ocular GVHD and similar inflammatory ocular conditions.
