ANDREWS, STEVEN W.,BLAKE, JAMES F.,COOK, ADAM,GUNAWARDANA, INDRANI W.,HUNT, KEVIN W.,METCALF, ANDREW T.,MORENO, DAVID,REN, LI,TANG, TONY P.
申请号：
CA3002560
公开号：
CA3002560A1
申请日:
2016.10.24
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Provided herein are compounds of the general Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which X, R1, R2, R3, Ring A and z have the meanings given in the specification, which are inhibitors of FGFR1, FGFR2, FGFR3 and/or FGFR4 and are useful in the treatment and prevention of diseases which can be treated with an FGFR inhibitor, including diseases or disorders mediated by FGFR1, FGFR2, FGFR3 and/or FGFR4.
