Open implant constituted of an osteogenic composition comprising at least an osteogenic growth factor, a soluble divalent cation salt, and an organic support, where the organic support does not comprise demineralized bone matrix, is claimed. An independent claim is included for a process for preparation of the implant comprising first placing a solution comprising the osteogenic growth factor, second placing the organic matrix and/or polymer forming the hydrogel, first adding the solution containing the growth factor to the organic matrix and/or the hydrogel, and optionally homogenizing the mixture, second adding a solution of a soluble divalent cation salt to the obtained implant, and optionally processing freeze-drying of the obtained implant. ACTIVITY : Osteopathic. MECHANISM OF ACTION : None given.
