Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compostions comprising them are disclosed； the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer.揭示式(I)經取代之吲唑衍生物及其醫藥上可接受之鹽，定義係如本說明書所述、其製備方法及包含其之醫藥組成物；本發明化合物可用於與蛋白質激酶活性失調相關之疾病例如癌症之治療。
