Gregor James MacDonald,Johannes Wilhelmus John F. Thuring,Pauline Carol Stanislawski,Wei Zhuang,Yves Emiel Maria Van Roosbroeck,Frans Alfons Maria Van Den Keybus
申请号：
US12866054
公开号：
US08778974B2
申请日:
2009.03.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to 1-aryl-3-aniline-5-alkyl-1,2,4-triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I).The invention particularly relates to potent positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.
