Johannes Wilhelmus John F. Thuring,Theodorus Dinklo,Anne Simone Josephine Lesage,Marcel Frans Leopold De Bruyn,Wei Zhuang
申请号：
US12738763
公开号：
US08440701B2
申请日:
2008.10.15
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to substituted 1-(alkyl)-3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I).The invention particularly relates to potent positive allosteric modulators of nicotinic acetylcholine receptors which have the capability of increasing the efficacy of nicotinic receptor agonists.
