Johannes Wilhelmus John F. Thuring,Gregor James MacDonald,Anne Simone Josephine Lesage,Wei Zhuang,Marcel Frans Leopold De Bruyn,Frans Alfons Maria Van Den Keybus,Yves Emiel Maria Van Roosbroeck,Theodo
申请号:
US12297059
公开号:
US08143419B2
申请日:
2007.04.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to 3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I).The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.