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trisubstituted pyrazoles as acetylcholine receptor modulators.
专利权人:
JANSSEN PHARMACEUTICA N.V.
发明人:
GREGOR JAMES MACDONALD,JOHANNES WILHELMUS JOHN F. THURING,WEI ZHUANG
申请号:
BRPI0912196
公开号:
BRPI0912196A2
申请日:
2009.05.08
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The present invention relates to 1-alkyl-3-aniline-5-aryl-pyrazole derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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