Johannes Wilhelmus John F. Thuring;Gregor James MacDonald;Wei Zhuang
发明人:
Johannes Wilhelmus John F. Thuring,Gregor James MacDonald,Wei Zhuang
申请号：
US12991119
公开号：
US08779158B2
申请日:
2009.05.08
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to 1-alkyl-3-aniline-5-aryl-pyrazole derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I).The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.
